Krebs citric acid cycle

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Definition

Noun: - Krebs citric acid cycle: A fundamental metabolic pathway occurring in the mitochondria of all plants and animals. It is a series of enzymatic reactions that completes the oxidation of acetyl compounds derived from carbohydrates, fats, and proteins, producing high-energy phosphate compounds (like ATP) and reducing agents (like NADH) that are the primary sources of cellular energy. It is also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle.

Usage

The term is used in scientific contexts, particularly in biochemistry, biology, and medicine, to describe this central energy-producing cycle. - The Krebs citric acid cycle is a crucial stage in aerobic respiration. - Understanding the regulation of the Krebs citric acid cycle is essential for studying cellular metabolism.

Advanced Usage
  • "to enter the Krebs citric acid cycle": Refers to the point where acetyl-CoA, derived from various nutrients, begins the cyclic series of reactions.
    • Pyruvate is converted to acetyl-CoA before it can enter the Krebs citric acid cycle.
Variants and Related Words
  • Krebs cycle (n): A common abbreviated name for the Krebs citric acid cycle.
  • Tricarboxylic acid cycle (TCA cycle) (n): Another scientific synonym for the Krebs citric acid cycle.
  • Citric acid cycle (n): A name emphasizing the first product of the cycle, citric acid.
Synonyms
  • Tricarboxylic acid cycle (TCA cycle)
  • Krebs cycle
  • Citric acid cycle
Related Phrases
  • Oxidative phosphorylation: The subsequent metabolic process that uses the products of the Krebs citric acid cycle (NADH, FADH₂) to produce most of the cell's ATP.
    • The high-energy electrons carried by NADH from the Krebs citric acid cycle drive oxidative phosphorylation.
Noun
  1. in all plants and animals: a series of enzymatic reactions in mitochondria involving oxidative metabolism of acetyl compounds to produce high-energy phosphate compounds that are the source of cellular energy